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Getting up in the morning

Humans

Early risers may have inherited faster body clocks from Neanderthals

Modern humans who have inherited genetic variants related to circadian rhythms from extinct hominins are more likely to be morning people

Light micrograph of a section through the spleen of a patient with Gaucher's disease. Small lymphocytes and large macrophage cells (Gaucher?s cells, pink, a type of white blood cell) are present. Gaucher's disease is an inherited metabolic disorder in which a fatty substance called glucocerebroside accumulates in the spleen (in macrophages), lungs, liver and bone marrow, and sometimes the brain. This is due to an absence of the enzyme glucocerebrosidase (GC). The disease appears in childhood, and some forms are fatal in the first few years. Other forms cause enlargement of the affected organs, weak and painful bones and anaemia. Some forms also cause severe nervous system damage. There is no cure, but enzyme replacement therapy using GC can relieve the symptoms. Haematoxylin-eosin saffron (HES) stain. Magnification: x400 at 24x36 mm size.

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Genes for Gaucher disease may have protected Jewish people against TB

Wine bottle and wine Glass

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Why gene variant impairing alcohol breakdown raises heart disease risk

Electron microscope image of SARS-CoV-2 coronavirus particles

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Genetic tracking scheme for viruses could warn of dangerous outbreaks

Genetics may influence the risk of pre-eclampsia or high blood pressure in pregnancy

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Pre-eclampsia and hypertension in pregnancy linked to 19 gene variants

DNA

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Parasitic DNA makes us age faster – but we’re not sure why

X-ray of feet affected by gout

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Gout linked to 376 genetic variants in a study of 2.6 million people

Environment

The surprising origin of sprouts, the vegetable we either love or hate

Visualizing inferred human ancestral lineages over time and space. Each line represents an ancestor-descendant relationship in our inferred genealogy of modern and ancient genomes. The width of a line corresponds to how many times the relationship is observed, and lines are colored on the basis of the estimated age of the ancestor.

Humans

A family tree of humanity released in 2022 shows how we’re all related

Amyloid plaques forming between neurons. Beta-amyloid protein disrupting nerve cells function in a brain with Alzheimer's disease

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Alzheimer鈥檚 disease progression slowed using CRISPR technique in mice

Removing only a small segment of a gene in the brain cells of mice reduced the formation of plaques seen in Alzheimer鈥檚 disease by 44 per cent

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Thousands of genetic variants may influence smoking and alcohol use

Life

DNA from 2 million years ago is the oldest ever recovered

Life

‘Unselfish’ genes that make plants cooperate could boost crop yields

Life

A rat without a Y chromosome could be a glimpse of our genetic future